| Name | LytA |
| Recommended Name ? | autolysin |
| Systematic Name ? | peptidoglycan amidohydrolase |
| Alternative Name ? | autolysin LytA
acetylmuramoyl-alanine amidase acetylmuramyl-alanine amidase acetylmuramyl-L-alanine amidase N-acetylmuramic acid L-alanine amidase N-acetylmuramyl-L-alanine amidase N-acetylmuramylalanine amidase N-acylmuramyl-L-alanine amidase peptidoglycan amidohydrolase |
| Uniprot ID | P06653 |
| General Mode of Action | Enzymatic cleavage of peptidoglycan which results in a rapid lysis of the bacterial cell (destruction of pneumococcal cells strictly depends on the presence of choline). |
| phiBIOTICS Family ? | NAM amidase |
| Reaction ? | 1. Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides (R04112) EC: 3.5.1.28 Corresponding Pfam domain: Amidase_2 Evidence: experimental (PubMed: 4149515) |
| Source Organism ? | Streptococcus pneumoniae |
| Target Organism ? | Streptococcus pneumoniae |
| Disease ? | Meningitis Otitis media Pneumonia Septicemia |
| State ? | Tested |
| Reference ? | 2875013 4149515 |